ChemicalBook--->CAS DataBase List--->136132-77-9

136132-77-9

136132-77-9 Structure

136132-77-9 Structure
IdentificationBack Directory
[Name]

BOC-ARG-VAL-ARG-ARG-AMC
[CAS]

136132-77-9
[Synonyms]

BOC-RVRR-AMC
BOC-ARG-VAL-ARG-ARG-AMC
Boc-Arg-Val-Arg-Arg-AMC(hydrochloride)
BOC-ARG-VAL-ARG-ARG-7-AMIDO-4-METHYLCOUMARIN
N-T-boc-arg-val-arg-arg 7-amido-4-*methylcoumarin
N-BOC-Arg-Val-Arg-Arg-7-amido-4-methylcoumarin acetate
Boc-Arg-Val-Arg-Arg-7-amido-4-methylcoumarin acetate salt
L-Argininamide,N2-[(1,1-dimethylethoxy)carbonyl]-L-arginyl-L-valyl-L-arginyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-,monohydrochloride
[Molecular Formula]

C38H62N14O8
[MDL Number]

MFCD00237533
[MOL File]

136132-77-9.mol
[Molecular Weight]

842.99
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

White to off-white powder.
[color ]

White to off-white
[Sequence]

{Boc-Arg}-Val-Arg-{Arg-AMC}
Hazard InformationBack Directory
[Uses]

Boc-Arg-Val-Arg-Arg-AMC hydrochloride (Boc-RVRR-AMC) is a synthetic fluorogenic substrate that is efficiently cleaved by furin[1].
[References]

[1] Wanyiri JW, et al. Proteolytic processing of the Cryptosporidium glycoprotein gp40/15 by human furin and by a parasite-derived furin-like protease activity. Infect Immun. 2007 Jan;75(1):184-92. DOI:10.1128/IAI.00944-06
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