| Identification | Back Directory | [Name]
Ac4GlcNAl | [CAS]
1361993-37-4 | [Synonyms]
Ac4GlcNAl
Ac4GlcNAI
Ac4GlcNAlk
N-(4-pentynoyl)-glucosamine tetraacylated
N-(4-pentynoyl)-glucosamine-tetraacylated (Ac4GlcAl)
2-deoxy-2-[(1-oxo-4-pentyn-1-yl)amino]-1,3,4,6-Tetraacetate-D-Glucopyranose
2-deoxy-2-[(1-oxo-4- pentyn-1-yl) amino] -2- deoxy-1,3,4,6-tetra-O- acetyl-D-glucopyranose | [Molecular Formula]
C19H25NO10 | [MDL Number]
MFCD32857621 | [MOL File]
1361993-37-4.mol | [Molecular Weight]
427.4 |
| Chemical Properties | Back Directory | [Boiling point ]
570.1±50.0 °C(Predicted) | [density ]
1.28±0.1 g/cm3(Predicted) | [solubility ]
Soluble to 100 mM in DMSO | [pka]
12.63±0.70(Predicted) | [Appearance]
beige powder |
| Hazard Information | Back Directory | [Description]
Ac4GlcNAl is an unnatural alkyne-containing monosaccharide building block. The alkyne moiety can be used for modification though chemoselective ligation chemistries including CuAAC or various Pd-catalyzed coupling reactions. The acetyl groups increase solubility in many solvents and make handling of this reagent easier. | [Uses]
Ac4GlcNAlk is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
Alkyl-Chain | [storage]
Store at -20°C | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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| Company Name: |
GlycoPharm.LLC
|
| Telephone: |
+86-27-63498076 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList909933/0_EN.htm |
| Company Name: |
Bide Pharmatech Ltd.
|
| Telephone: |
400-1647117 13681763483 |
| Website: |
https://www.bidepharm.com/ |
|