| Identification | Back Directory | [Name]
FIBRONECTIN CS-1 FRAGMENT (1978-1985) | [CAS]
136466-51-8 | [Synonyms]
EILDVPST
FIBRONECTIN CS-1 PEPTIDE
Fibronectin CS-1 Peptide (3)
GLU-ILE-LEU-ASP-VAL-PRO-SER-THR
H-GLU-ILE-LEU-ASP-VAL-PRO-SER-THR-OH
FIBRONECTIN CS-1 FRAGMENT (1978-1985)
Fibronectin CS-1 FragMent (1978-1985)
EILDVPST
L-Threonine, L-α-glutamyl-L-isoleucyl-L-leucyl-L-α-aspartyl-L-valyl-L-prolyl-L-seryl- | [Molecular Formula]
C38H64N8O15 | [MDL Number]
MFCD00080351 | [MOL File]
136466-51-8.mol | [Molecular Weight]
872.96 |
| Chemical Properties | Back Directory | [Boiling point ]
1306.0±65.0 °C(Predicted) | [density ]
1.317±0.06 g/cm3(Predicted) | [storage temp. ]
-15°C
| [form ]
Solid | [pka]
3.16±0.10(Predicted) | [Sequence]
Glu-Ile-Leu-Asp-Val-Pro-Ser-Thr |
| Hazard Information | Back Directory | [Uses]
The connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. Fibronectin CS1 Peptide lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontaneous and experimental metastasis models[1]. | [References]
[1] Saiki I, et al. Inhibition of lung metastasis by synthetic and recombinant fragments of human fibronectin with functional domains. Jpn J Cancer Res. 1990 Oct;81(10):1003-11. DOI:10.1111/j.1349-7006.1990.tb03338.x |
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