| Identification | Back Directory | [Name]
Unii-5H2DV04I6O | [CAS]
1369412-66-7 | [Synonyms]
DS-3801b
Unii-5H2DV04I6O
Cyclohexanecarboxamide, 4-[3-(hydroxymethyl)phenoxy]-N-methyl-N-[3-methyl-4-[[(3S)-3-methyl-1-piperazinyl]methyl]phenyl]-, trans- | [Molecular Formula]
C28H39N3O3 | [MOL File]
1369412-66-7.mol | [Molecular Weight]
465.63 |
| Chemical Properties | Back Directory | [Boiling point ]
639.2±55.0 °C(Predicted) | [density ]
1.148±0.06 g/cm3(Predicted) | [solubility ]
DMSO: Soluble: =10 mg/ml
Ethanol: Soluble: =10 mg/ml | [form ]
Solid | [pka]
14.29±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
DS-3801b is a potent and non-macrolide agonist of GPR38. DS-3801b is expected to be novel gastrointestinal prokinetic agents for the research of functional gastrointestinal disorders such as gastroparesis and chronic constipation[1]. | [References]
[1] Toda N, et al. Discovery of DS-3801b, a non-macrolide GPR38 agonist with N-methylanilide structure. Bioorg Med Chem Lett. 2022;59:128554. DOI:10.1016/j.bmcl.2022.128554 |
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