| Identification | Back Directory | [Name]
Rivaroxaban Impurity 27 | [CAS]
1369969-44-7 | [Synonyms]
Rivaroxaban Impurity 27
2-[(2S)-2-hydroxy-3-[4-(3-oxomorpholin-4-yl)anilino]propyl]isoindole-1,3-dione
1H-Isoindole-1,3(2H)-dione, 2-[(2S)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-
Rivaroxaban Impurity 13/2-[(2S)-2-Hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione | [Molecular Formula]
C21H21N3O5 | [MDL Number]
MFCD23104293 | [MOL File]
1369969-44-7.mol | [Molecular Weight]
395.41 |
| Chemical Properties | Back Directory | [Boiling point ]
734.9±60.0 °C(Predicted) | [density ]
1.421±0.06 g/cm3(Predicted) | [storage temp. ]
-10 to -25°C | [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated) | [form ]
Solid | [pka]
13.91±0.20(Predicted) | [color ]
White to Off-White | [Major Application]
pharmaceutical small molecule | [InChI]
1S/C21H21N3O5/c25-16(12-24-20(27)17-3-1-2-4-18(17)21(24)28)11-22-14-5-7-15(8-6-14)23-9-10-29-13-19(23)26/h1-8,16,22,25H,9-13H2/t16-/m0/s1 | [InChIKey]
CKFVSMPWXAASIQ-INIZCTEOSA-N | [SMILES]
N4(CCOCC4=O)c1ccc(cc1)NC[C@H](O)CN2C(=O)c3c(cccc3)C2=O |
| Hazard Information | Back Directory | [Uses]
2-[(2S)-2-Hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione is an intermediate in the synthesis of ent-Rivaroxaban (R538005), the R-isomer of Rivaroxaban (R538000), which is a novel antithrombotic agent. |
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