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137018-54-3

137018-54-3 Structure

137018-54-3 Structure
IdentificationBack Directory
[Name]

okicenone
[CAS]

137018-54-3
[Synonyms]

okicenone
3,4-Dihydro-4,6,9-trihydroxy-8-methylanthracen-1(2H)-one
1(2H)-Anthracenone, 3,4-dihydro-4,6,9-trihydroxy-8-methyl-
[Molecular Formula]

C15H14O4
[MDL Number]

MFCD00906973
[MOL File]

137018-54-3.mol
[Molecular Weight]

258.27
Hazard InformationBack Directory
[Description]

Okicenone is an antibiotic, interferring with HuR RNA binding, HuR trafficking, cytokine expression and T-cell activation.
[Uses]

Okicenone is a Hu protein R (HuR) inhibitor. Okicenone inhibits HuR oligomerization, interferes with HuR RNA binding, HuR trafficking, cytokine expression and T-cell activation[1].
[References]

[1] Meisner NC, et al. Identification and mechanistic characterization of low-molecular-weight inhibitors for HuR. Nat Chem Biol. 2007 Aug;3(8):508-15. DOI:10.1038/nchembio.2007.14
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