ChemicalBook--->CAS DataBase List--->1370468-36-2

1370468-36-2

1370468-36-2 Structure

1370468-36-2 Structure
IdentificationBack Directory
[Name]

Elbasvir
[CAS]

1370468-36-2
[Synonyms]

Elbasvir
Albasvir
Elbasvir/MK-8742
MK-8742 Elbasvir
MK-8742; MK8742; MK 8742
Carbamic acid, N,N'-[[(6S)-6-phenyl-6H-indolo[1,2-c][1,3]benzoxazine-3,10-diyl]bis[1H-imidazole-5,2-diyl-(2S)-2,1-pyrrolidinediyl[(1S)-1-(1-methylethyl)-2-oxo-2,1-ethanediyl]]]bis-, C,C'-dimethyl ester
[Molecular Formula]

C49H55N9O7
[MDL Number]

MFCD28124343
[MOL File]

1370468-36-2.mol
[Molecular Weight]

882.017
Chemical PropertiesBack Directory
[density ]

1.40±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

DMF: 33 mg/ml; DMSO: 20 mgm/l; Ethanol: 33 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.33 mg/ml
[form ]

A crystalline solid
[pka]

11.22±0.46(Predicted)
[color ]

White to yellow
Safety DataBack Directory
[Symbol(GHS) ]

Flame (GHS02)
GHS02
[Signal word ]

Warning
[Hazard statements ]

H226
[Precautionary statements ]

P501-P240-P210-P233-P243-P241-P242-P280-P370+P378-P303+P361+P353-P403+P235
Hazard InformationBack Directory
[Uses]

Elbasvir is a pharmaceutical drug that is used in the treatment of hepatitis C virus in patients with HCV genotype 1 infection. It inhibits an important viral phosphoprotein, NS5A, which is involved in viral replication, assembly, and secretion.
[Definition]

ChEBI: A complex organic heterotetracyclic compound that is a hepatitis C virus nonstructural protein 5A inhibitor used in combination with grazoprevir (under the brand name Zepatier) for treatment of chronic HCV genotypes 1 or 4 infection in adults.
Spectrum DetailBack Directory
[Spectrum Detail]

Elbasvir(1370468-36-2)1HNMR
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