| Identification | Back Directory | [Name]
4H-Naphtho[2,3-b]pyran-4-one, 6-(β-D-glucopyranosyloxy)-5,8-dihydroxy-2-methyl- | [CAS]
13709-03-0 | [Synonyms]
4H-Naphtho[2,3-b]pyran-4-one, 6-(β-D-glucopyranosyloxy)-5,8-dihydroxy-2-methyl- | [Molecular Formula]
C20H20O10 | [MDL Number]
MFCD13195556 | [MOL File]
13709-03-0.mol | [Molecular Weight]
420.37 |
| Chemical Properties | Back Directory | [Melting point ]
256-257 °C(Solv: acetone (67-64-1)) | [Boiling point ]
775.3±60.0 °C(Predicted) | [density ]
1.660±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
6.06±0.40(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
Cassiaside is a naphthopyrone glucoside, shows mixed-type inhibition against BACE1 (IC50=4.45 μM; Ki=9.85 μM). Cassiaside possesses potential anti- Alzheimer's disease (AD) activity[1]. | [Definition]
ChEBI: Cassiaside is a glycoside and a benzochromenone. | [References]
[1] Jung HA, et al. Inhibitory activities of major anthraquinones and other constituents from Cassia obtusifolia against β-secretase and cholinesterases. J Ethnopharmacol. 2016;191:152-160. DOI:10.1016/j.jep.2016.06.037 |
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