| Identification | Back Directory | [Name]
APTIGANEL HYDROCHLORIDE | [CAS]
137159-92-3 | [Synonyms]
CERESTAT
CNS-1102
Aptiganel [inn]
Unii-46475lv84i
APTIGANEL HYDROCHLORIDE
1-(m-Ethylphenyl)-1-methyl-3-(1-naphthyl)guanidine
N-(3-ETHYLPHENYL)-N-METHYL-N''-1-NAPHTHALENYLGUANIDINE HYDROCHLORIDE
Aptiganel hydrochloride, Cerestat, N-(3-Ethylphenyl)-N-methyl-N-1-naphthalenylguanidine hydrochloride | [Molecular Formula]
C20H21N3 | [MDL Number]
MFCD00867728 | [MOL File]
137159-92-3.mol | [Molecular Weight]
303.4 |
| Chemical Properties | Back Directory | [Boiling point ]
455.1±38.0 °C(Predicted) | [density ]
1.08±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
H2O: 17 mg/mL, soluble | [form ]
solid | [pka]
12.44±0.30(Predicted) | [color ]
white | [Water Solubility ]
H2O: 17mg/mL | [InChI]
1S/C20H21N3/c1-3-15-8-6-11-17(14-15)23(2)20(21)22-19-13-7-10-16-9-4-5-12-18(16)19/h4-14H,3H2,1-2H3,(H2,21,22) | [InChIKey]
BFNCJMURTMZBTE-UHFFFAOYSA-N |
| Hazard Information | Back Directory | [Uses]
Stroke and
traumatic brain injury treatment (NMDA ion channel
blocker). | [Definition]
ChEBI: Aptiganel is a member of naphthalenes. | [Brand name]
Cerestat (Cambridge). | [Biological Activity]
Primary Target
NMDA receptors''Target IC50: 0.130.0680.087and 0.14 μM for NR2A –Drespectively. |
|
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
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