| Identification | Back Directory | [Name]
FIBRINOGEN-BINDING PEPTIDE | [CAS]
137235-80-4 | [Synonyms]
EHIPA
GLU-HIS-ILE-PRO-ALA
H-GLU-HIS-ILE-PRO-ALA-OH
FIBRINOGEN-BINDING PEPTIDE
Fibrinogen-Binding Peptide (3)
glutamyl-histidyl-isoleucyl-prolyl-alanine
L-α-Glutamyl-L-histidyl-L-isoleucyl-L-prolyl-L-alanine | [Molecular Formula]
C25H39N7O8 | [MDL Number]
MFCD00214608 | [MOL File]
137235-80-4.mol | [Molecular Weight]
565.62 |
| Chemical Properties | Back Directory | [Boiling point ]
1067.8±65.0 °C(Predicted) | [density ]
1.343±0.06 g/cm3(Predicted) | [storage temp. ]
-15°C | [form ]
Solid | [pka]
3.70±0.10(Predicted) | [color ]
White to off-white | [Sequence]
Glu-His-Ile-Pro-Ala |
| Hazard Information | Back Directory | [Uses]
Fibrinogen-Binding Peptide (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide binds fibrinogen and inhibits both the adhesion of platelets to fibrinogen and platelet aggregation, and also inhibits the adhesion of platelets to vitronectin[1]. | [References]
[1] Gartner TK, et al. The peptide Glu-His-Ile-Pro-Ala binds fibrinogen and inhibits platelet aggregation and adhesion to fibrinogen and vitronectin. Proc Soc Exp Biol Med. 1991 Oct;198(1):649-55. DOI:10.3181/00379727-198-43303 |
|
| Company Name: |
Ontores Biotech
|
| Telephone: |
0571-88760729 18072970094 |
| Website: |
www.ontoresinc.cn |
|