| Chemical Properties | Back Directory | [storage temp. ]
-20°, stored under nitrogen,unstable in solution, ready to use. | [solubility ]
DMSO: 210 mg/mL (596.12 mM) | [form ]
Solid | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
Sulfo-ara-F-NMN (CZ-48) is a mimetic of nicotinamide mononucleotide (NMN). Sulfo-ara-F-NMN acts selectively, activating SARM1 but inhibiting CD38 (IC50 around 10 μM). Sulfo-ara-F-NMN induces intracellular cyclic ADP-ribose (cADPR) production[1]. | [storage]
-20°, stored under nitrogen,unstable in solution, ready to use. | [References]
[1] Zhao ZY, et al. A Cell-Permeant Mimetic of NMN Activates SARM1 to Produce Cyclic ADP-Ribose and Induce Non-apoptotic Cell Death. iScience. 2019 May 31;15:452-466. DOI:10.1016/j.isci.2019.05.001 |
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MedChemExpress
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021-58955995 |
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www.medchemexpress.com |
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