| Identification | Back Directory | [Name]
Maytansine, N2'-deacetyl-N2'-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]- | [CAS]
1375089-56-7 | [Synonyms]
MC-DM1
Maytansine, N2'-deacetyl-N2'-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]- | [Molecular Formula]
C42H55ClN4O12 | [MDL Number]
MFCD32874114 | [MOL File]
1375089-56-7.mol | [Molecular Weight]
843.37 |
| Chemical Properties | Back Directory | [Boiling point ]
1007.8±65.0 °C(Predicted) | [density ]
1.34±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
9.82±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
MC-DM1 is a agent-linker conjugate composed of a potent microtubule-disrupting agent DM1 and a linker MC to make antibody agent conjugate (ADC)[1]. | [IC 50]
Maytansinoids | [References]
[1] Shao S, et al. Site-specific and hydrophilic ADCs through disulfide-bridged linker and branched PEG. Bioorg Med Chem Lett. 2018 May 1;28(8):1363-1370. DOI:10.1016/j.bmcl.2018.03.005 |
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