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1379604-68-8

1379604-68-8 Structure

1379604-68-8 Structure
IdentificationBack Directory
[Name]

JWH 122 N-(5-hydroxypentyl) metabolite
[CAS]

1379604-68-8
[Synonyms]

JWH 122 N-(5-hydroxypentyl) metabolite
[1-(5-hydroxypentyl)indol-3-yl]-(4-methylnaphthalen-1-yl)methanone
Methanone, [1-(5-hydroxypentyl)-1H-indol-3-yl](4-methyl-1-naphthalenyl)-
[Molecular Formula]

C25H25NO2
[MDL Number]

MFCD27966186
[MOL File]

1379604-68-8.mol
[Molecular Weight]

371.47
Chemical PropertiesBack Directory
[Boiling point ]

607.8±40.0 °C(Predicted)
[density ]

1.14±0.1 g/cm3(Predicted)
[solubility ]

DMF: 10 mg/ml; DMSO: 12.5 mg/ml; Ethanol: 10 mg/ml
[form ]

A crystalline solid
[pka]

15.17±0.10(Predicted)
Hazard InformationBack Directory
[Description]

JWH 122 is a synthetic cannabinoid (CB) of the naphthoylindole class that is structurally related to JWH 018 and JWH 073. It displays high-affinities for both CB1 (Ki = 0.69 nM) and CB2 (Ki = 1.2 nM) receptors. JWH 122 N-(5-hydroxypentyl) metabolite is a metabolite of JWH 122 that is characterized by monohydroxylation of the N-alkyl chain. Currently, there are no reports of its biological activity.
[Uses]

JWH-122 5-Hydroxypentyl is a urinary metabolite of JWH-122.
[References]

[1] LUDGER ERNST . Identification and characterization of JWH-122 used as new ingredient in “Spice-like” herbal incenses[J]. Forensic science international, 2011, 208 1: Pages e31-e35. DOI: 10.1016/j.forsciint.2011.03.020
[2] MELANIE HUTTER. Metabolism of Nine Synthetic Cannabinoid Receptor Agonists Encountered in Clinical Casework: Major in vivo Phase I Metabolites of AM-694, AM-2201, JWH-007, JWH-019, JWH-203, JWH-307, MAM-2201, UR-144 and XLR-11 in Human Urine Using LC-MS/MS.[J]. Current pharmaceutical biotechnology, 2018, 19 2: 144-162. DOI: 10.2174/1389201019666180509163114
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