| Identification | Back Directory | [Name]
(1-hexyl-5-hydroxyindol-3-yl)-naphthalen-1-ylmethanone | [CAS]
1379604-70-2 | [Synonyms]
(1-hexyl-5-hydroxyindol-3-yl)-naphthalen-1-ylmethanone
(1-hexyl-5-hydroxy-1H-indol-3-yl)(naphthalen-1-yl)-methanone
Methanone, (1-hexyl-5-hydroxy-1H-indol-3-yl)-1-naphthalenyl- | [Molecular Formula]
C25H25NO2 | [MOL File]
1379604-70-2.mol | [Molecular Weight]
371.47 |
| Hazard Information | Back Directory | [Description]
JWH 019 is a cannabimimetic indole that shows a high-affinity for both the central cannabinoid (CB) and the peripheral CB receptors.1 It has been detected in certain herbal blends sold for human consumption. JWH 019 5-hydroxyindole metabolite is expected to be a major metabolite of JWH 019, detectable in serum and urine.2,3 The biological effects of the metabolite are not known | [References]
1. Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding Drug Alcohol Depend. 60(2),133-140(2000).
2. Sobolevsky, T., Prasolov, I., and Rodchenkov, G. Detection of JWH-018 metabolites in smoking mixture post-administration urine Forensic Sci. Int. 200(1-3),141-147(2010).
3. Zhang, Q., Ma, P., Cole, R.B., et al. Identification of in vitro metabolites of JWH-015, an aminoalkylindole agonist for the peripheral cannabinoid receptor (CB2) by HPLC-MS/MS Anal. Bioanal. Chem. 386(5),1345-1355(2006). |
|
|