| Identification | Back Directory | [Name]
Acetamide, 2-[[(3-hydroxyestra-1,3,5(10)-trien-17-ylidene)amino]oxy]- (9CI) | [CAS]
138219-84-8 | [Synonyms]
ERα ligand 1
Estrone-N-O-C1-amido
Acetamide, 2-[[(3-hydroxyestra-1,3,5(10)-trien-17-ylidene)amino]oxy]- (9CI) | [Molecular Formula]
C20H26N2O3 | [MDL Number]
MFCD32062710 | [MOL File]
138219-84-8.mol | [Molecular Weight]
342.43 |
| Hazard Information | Back Directory | [Uses]
Estrone-N-O-C1-amido (ERα ligand 1) is an Estrone-based estrogen ligand, which targets estrogen receptor α (ERα). Estrone-N-O-C1-amido (ERα ligand 1) binds to cIAP1 ligand Bestatin via a linker to form SNIPER[1]. | [References]
[1] Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019 Jan 25;17:160-176. DOI:10.1016/j.csbj.2019.01.006 |
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