ChemicalBook--->CAS DataBase List--->138490-53-6

138490-53-6

138490-53-6 Structure

138490-53-6 Structure
IdentificationBack Directory
[Name]

WAY 123398
[CAS]

138490-53-6
[Synonyms]

Way123
Way-123
Way 123
WAY 123398
WAY-123398 free base
[Molecular Formula]

C19H25N5O4S2
[MDL Number]

MFCD00905024
[MOL File]

138490-53-6.mol
[Molecular Weight]

451.56
Chemical PropertiesBack Directory
[Boiling point ]

637.9±65.0 °C(Predicted)
[density ]

1.36±0.1 g/cm3(Predicted)
[pka]

6.93±0.10(Predicted)
Hazard InformationBack Directory
[Description]

Way 123398 is a class III antiarrhythmic agent.
[Uses]

WAY-123398 is a class III antiarrhythmic agent. WAY-123398 is a selective blocker of the delayed rectifier K+ current[1].
[References]

[1] Spinelli W, et al. Cellular electrophysiology of WAY-123,398, a new class III antiarrhythmic agent: specificity of IK block and lack of reverse use dependence in cat ventricular myocytes. Cardiovasc Res. 1993 Sep;27(9):1580-91. DOI:10.1093/cvr/27.9.1580
[2] Spinelli W,et al. Effects of WAY-123,398, a new class III antiarrhythmic agent, on cardiac refractoriness and ventricular fibrillation threshold in anesthetized dogs: a comparison with UK-68798, E-4031, and dl-sotalol. J Cardiovasc Pharmacol. 1992 Dec;20(6):913-22. DOI:10.1097/00005344-199212000-00011
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