1386811-71-7

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1386811-71-7 Structure

Chemical Properties	Back Directory
[density ] 1.41±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[form ] Solid
[pka] 11.70±0.70(predicted)
[color ] White to off-white

Hazard Information	Back Directory
[Uses] GA32 (compound 58r) is potent androgen receptor (AR)/glucocorticoid receptor (GR) dual inhibitor with IC50 values of 0.13 μM and 0.83 μM for AR and GR, respectively. GA32 inhibits the proliferation of Enzalutamide (HY-70002) resistance castration-resistant prostate cancer both in vitro and in vivo[1].
[References] [1] Li C, et al. Design and Synthesis of Dual-Target Inhibitors Targeting Androgen Receptors and Glucocorticoid Receptors to Overcome Antiandrogen Resistance in Castration-Resistant Prostate Cancer. J Med Chem. 2024 Feb 22. DOI:10.1021/acs.jmedchem.3c01668

1386811-71-7 suppliers list

Company Name:	Shanghai Chaolan Chemical Technology Center
Tel:	021-QQ：65489617 15618227136
Website:	www.atkchemical.com/

Company Name:	Jinan Jiuli Biotechnology Co. , Ltd.
Tel:	15865264761
Website:	www.chemicalbook.com/ShowSupplierProductsList89365/0_EN.htm

Company Name:	AnEasyTech Shanghai Co., Ltd.
Tel:	13916181326
Website:	https://www.chemicalbook.com/ShowSupplierProductsList1032212/0_EN.htm

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