Chemical Properties | Back Directory | [Boiling point ]
541.6±30.0 °C(Predicted) | [density ]
1.048±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [form ]
Solid | [pka]
4.67±0.33(Predicted) | [color ]
Light yellow to yellow |
Hazard Information | Back Directory | [Uses]
(6E)-SR 11302 is a E-isomer of SR 11302. SR 11302 is an activator protein-1 (AP-1) transcription factor inhibitor. SR 11302 is a retinoid that specifically inhibits AP-1 activity without activating the transcription of retinoic acid response element (RARE)[1]. | [References]
[1] C Huang, et al. Blocking activator protein-1 activity, but not activating retinoic acid response element, is required for the antitumor promotion effect of retinoic acid. Proc Natl Acad Sci U S A. 1997 May 27;94(11):5826-30. DOI:10.1073/pnas.94.11.5826 |
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guoyungurui
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