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139066-77-6

139066-77-6 Structure

139066-77-6 Structure
IdentificationBack Directory
[Name]

dorzolamide
[CAS]

139066-77-6
[Synonyms]

(4S, 6R)-Dorzolamide EP Impurity B
4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, (4S-cis)-
[Molecular Formula]

C10H16N2O4S3
[MOL File]

139066-77-6.mol
[Molecular Weight]

324.44
Hazard InformationBack Directory
[Definition]

ChEBI: Dorzolamide is 5,6-Dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide in which hydrogens at the 4 and 6 positions are substituted by ethylamino and methyl groups, respectively (4S, trans-configuration). A carbonic anhydrase inhibitor, it is used as the hydrochloride in ophthalmic solutions to lower increased intraocular pressure in the treatment of open-angle glaucoma and ocular hypertension. It has a role as an EC 4.2.1.1 (carbonic anhydrase) inhibitor, an antihypertensive agent and an antiglaucoma drug. It is a sulfonamide and a member of thiophenes.
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