| Identification | Back Directory | [Name]
PC cell-derived growth factor | [CAS]
NoCAS | [Synonyms]
PEPI
TIM4
TIMD4
Proepithelin
Progranulin rat
Progranulin mouse
Progranulin from mouse
Tim-4 (human): FC (human)
T-cell membrane protein 4
PC cell-derived growth factor
Activation-inducible TNF-related ligand |
| Hazard Information | Back Directory | [Uses]
Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimer′s Disease (AD) and potentially for MCI (Mild Cognitive Impairment). Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis. |
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| Company Name: |
Biolab Reagents
|
| Tel: |
65279366 18108604356 |
| Website: |
www.biolabreagent.com/ |
| Company Name: |
ACROBiosystems
|
| Tel: |
13121935750 |
| Website: |
https://www.acrobiosystems.cn/?utm_source=chemical book&utm_medium=cpy&utm_campaign=chemical book official web site |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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