| Identification | Back Directory | [Name]
1H-Isoindole-1,3(2H)-dione, 2-[3-[[2-(4-methylphenyl)-2-oxoethyl]thio]-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-4-yl]- | [CAS]
1394017-46-9 | [Synonyms]
Tubulin polymerization-IN-7
1H-Isoindole-1,3(2H)-dione, 2-[3-[[2-(4-methylphenyl)-2-oxoethyl]thio]-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-4-yl]- | [Molecular Formula]
C28H24N4O6S | [MOL File]
1394017-46-9.mol | [Molecular Weight]
544.58 |
| Hazard Information | Back Directory | [Uses]
Tubulin polymerization-IN-7 (compound 5) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-7 has the potential for the research of cancer diseases[1]. | [References]
[1] Chen L, et al. Concise synthesis and preliminary biological evaluation of new triazolylthioacetone derivatives bearing pyridine, pyrazine, and 3,4,5-trimethoxybenzyl fragment. Bioorg Med Chem Lett. 2022;66:128721. DOI:10.1016/j.bmcl.2022.128721 |
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