| Questions And Answer | Back Directory | [Description]
Lurasidone hydrochloride is the hydrochloride form of Lurasidone. It is an atypical antipsychotic. It is indicated for the treatment of schizophrenia, depressive episode associated with bipolar I disorder in adults when used alone or in combination with lithium or valproate. Lurasidone is a benzothiazol derivative that is an antagonist and binds with high affinity to Dopamine-2, 5-HT2A receptor, and 5-H7 receptors. It is generally thought that antagonism of serotonin receptors can improve the negative symptoms of psychoses and reduce the extrapyramidal side effects associated with typical antipsychotics.
| [References]
Nakamura, M, et al. "Lurasidone in the treatment of acute schizophrenia: a double-blind, placebo-controlled trial." Journal of Clinical Psychiatry70.6(2009):829.
Meyer, J. M., A. D. Loebel, and E. Schweizer. "Lurasidone: a new drug in development for schizophrenia." Expert Opinion on Investigational Drugs18.11(2009):1715.
https://en.wikipedia.org/wiki/Lurasidone
https://www.drugbank.ca/drugs/DB08815
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