| Identification | Back Directory | [Name]
1H-Pyrazole-3,5-dicarboxaMide | [CAS]
1397683-79-2 | [Synonyms]
1H-Pyrazole-3,5-dicarboxaMide
1H-Pyrazole-3,5-dicarboxylic acid diamide | [Molecular Formula]
C5H6N4O2 | [MDL Number]
MFCD24645956 | [MOL File]
1397683-79-2.mol | [Molecular Weight]
154.13 |
| Chemical Properties | Back Directory | [Boiling point ]
617.2±40.0 °C(Predicted) | [density ]
1.566±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
9.52±0.10(Predicted) |
| Hazard Information | Back Directory | [Synthesis]
General procedure for the synthesis of 1H-pyrazole-3,5-dicarboxamide from diethyl 1H-pyrazole-3,5-dicarboxylate:
Preparation of Example A55 Intermediate A59: 1H-pyrazole-3,5-dicarboxamide
Diethyl 1H-pyrazole-3,5-dicarboxylate (5.2 g, 24.5 mmol) was dissolved in a methanol solution of 7 M ammonia (1/4 volume) and the mixture was transferred to a sealed tube and the reaction was heated at 70 °C for 48 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure to afford intermediate A59 (3.74 g, 99% yield) as a solid. | [References]
[1] Patent: WO2012/117027, 2012, A1. Location in patent: Page/Page column 47 |
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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