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L 694746 is a HIV-1 protease inhibitor. | [Uses]
L 694746 is the metabolite of L-689502 (HY-U00261). L 694746 is an inhibitor for HIV-1 protease with an IC50 of 1 nM and a Ki of 0.34 nM[1]. | [References]
[1] Lingham RB, et al. HIV-1 protease inhibitory activity of L-694,746, a novel metabolite of L-689,502. Biochem Biophys Res Commun. 1991 Dec 31;181(3):1456-61. DOI:10.1016/0006-291x(91)92103-q |
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