| Identification | Back Directory | [Name]
DBCO-sulfo-SE | [CAS]
1400191-52-7 | [Synonyms]
DBCO-sulfo-SE
DBCO-sulfo-NHS ester
DBCO-C6-Sulfo-NHS ester
DBCO-Sulfo-NHS ester sodium
DBCO-sulfo-NHS ester,DBCO-sulfo-SE
Dibenzocyclooctyne-sulfo-N-hydroxysuccinimidyl ester | [Molecular Formula]
C25H21N2NaO8S | [MDL Number]
MFCD22572669 | [MOL File]
1400191-52-7.mol | [Molecular Weight]
532.498 |
| Chemical Properties | Back Directory | [Melting point ]
240-260 °C | [storage temp. ]
-20°C | [form ]
Solid | [color ]
Off-white to yellow | [InChIKey]
NSZPURPXEZOXPC-UHFFFAOYSA-N | [SMILES]
C(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)(=O)CCCCC(=O)ON1C(CC(S(O)(=O)=O)C1=O)=O.[NaH] |
| Hazard Information | Back Directory | [Description]
DBCO-Sulfo-NHS ester is a water-soluble sulfocated reagent containing DBCO moiety. It can be used for simple and efficient labeling of antibodies, proteins and any other primary amine-bearing macromolecules with DBCO moiety in 100% aqueous buffers. DBCO is commonly used for copper-free Click Chemistry reactions. | [Uses]
Dibenzocyclooctyne-sulfo-N-hydroxysuccinimidyl ester may be used for the covalent modification of nano-sized metal-organic frameworks (NMOFs) with nucleic acids via click chemistry during the synthesis stimuli-responsive DNA-gated NMOFs. These NMOFs can act as carriers of a fluorescent agent or anticancer drug, making them highly useful in targeted drug release system. | [reaction suitability]
reaction type: click chemistry
reagent type: linker | [IC 50]
Cleavable Linker |
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| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
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