| Identification | Back Directory | [Name]
2-[(2E)-8-[5-(4,5-dihydroxy-4,6-dimethyl-oxan-2-yl)oxy-4-dimethylamino -6-methyl-oxan-2-yl]oxy-14-ethyl-10-hydroxy-15-[(5-hydroxy-3,4-dimetho xy-6-methyl-oxan-2-yl)oxymethyl]-1,5,9-trimethyl-4,12-dioxo-13,17-diox abicyclo[14.1.0]heptadec-2-en-7-yl]acetaldehyde | [CAS]
1402-83-1 | [Synonyms]
angolamycin
Tylosin, 2A-deoxy-12,13-epoxy-12,13-dihydro-, (1'ξ)-
2-[(2E)-8-[5-(4,5-dihydroxy-4,6-dimethyl-oxan-2-yl)oxy-4-dimethylamino -6-methyl-oxan-2-yl]oxy-14-ethyl-10-hydroxy-15-[(5-hydroxy-3,4-dimetho xy-6-methyl-oxan-2-yl)oxymethyl]-1,5,9-trimethyl-4,12-dioxo-13,17-diox abicyclo[14.1.0]heptadec-2-en-7-yl]acetaldehyde | [Molecular Formula]
C46H77NO17 | [MDL Number]
MFCD01670065 | [MOL File]
1402-83-1.mol | [Molecular Weight]
916.1 |
| Chemical Properties | Back Directory | [Melting point ]
134.5°C | [Boiling point ]
801.04°C (rough estimate) | [density ]
1.1406 (rough estimate) | [refractive index ]
1.5280 (estimate) | [color ]
Crystals from Et2O |
| Hazard Information | Back Directory | [Uses]
Angolamycin is a basic macrolide antibiotic active against Gram-positive bacteria[1]. | [Safety Profile]
Poison by several routes. Whenheated to decomposition it emits toxic fumes of NOx. | [References]
[1] Vazquez, D. (1967). Macrolide antibiotics-Spiramycin, Carbomycin, Angolamycin, Methymycin and Lancamycin. In: Gottlieb, D., Shaw, P.D. (eds) Mechanism of Action. Antibiotics, vol 1. Springer, Berlin, Heidelberg. |
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