| Identification | Back Directory | [Name]
Ca2+ channel agonist 1 | [CAS]
1402821-24-2 | [Synonyms]
Ca2+ channel agonist 1
1-Butanol, 2-[[6-[(phenylmethyl)amino]-9-propyl-9H-purin-2-yl]amino]-, (2R)- | [Molecular Formula]
C19H26N6O | [MOL File]
1402821-24-2.mol | [Molecular Weight]
354.45 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 50 mg/mL (141.06 mM);Water : < 0.1 mg/mL (insoluble) | [form ]
Solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2, with EC50s of 14.23 μM and 3.34 μM, respectively, and is used as a potential treatment for motor nerve terminal dysfunction. | [IC 50]
CDK2: 3.34 μM (EC50); N-type calcium channel: 14.23 μM (EC50) | [storage]
Store at -20°C | [References]
[1] Liang M, et al. Synthesis and biological evaluation of a selective N- and p/q-type calcium channel agonist. ACS Med Chem Lett. 2012 Oct 1;3(12):985-990. DOI:10.1021/ml3002083 |
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BOC Sciences
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1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
Musechem
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+1-800-259-7612 |
| Website: |
www.musechem.com |
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