ChemicalBook--->CAS DataBase List--->1403744-37-5

1403744-37-5

1403744-37-5 Structure

1403744-37-5 Structure
IdentificationBack Directory
[Name]

DSPE-PEG-COOH
[CAS]

1403744-37-5
[Synonyms]

DSPE-PEG-COOH
Poly(oxy-1,2-ethanediyl), α-(carboxymethyl)-ω-[[(10R)-7-hydroxy-7-oxido-2,13-dioxo-10-[(1-oxooctadecyl)oxy]-6,8,12-trioxa-3-aza-7-phosphatriacont-1-yl]oxy]-, sodium salt
Poly(oxy-1,2-ethanediyl), α-(carboxymethyl)-ω-[[(10R)-7-hydroxy-7-oxido-2,13-dioxo-10-[(1-oxooctadecyl)oxy]-6,8,12-trioxa-3-aza-7-phosphatriacont-1-yl]oxy]-, sodium salt (1:1)
[Molecular Formula]

(C2H4O)nC45H86NO12P.Na
[MOL File]

1403744-37-5.mol
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

water: soluble at 20 °C
[form ]

Solid
[color ]

White to off-white
[InChIKey]

CCALAKIQVJDGGW-UHFFFAOYSA-N
[SMILES]

C(COC(=O)CCCCCCCCCCCCCCCCC)(OC(=O)CCCCCCCCCCCCCCCCC)COP(O)(=O)OCCNC(=O)COC{-}CO{+n}CC(=O)O.[Na]
Hazard InformationBack Directory
[Description]

Mitoguazone dihydrochloride is a guanylhydrazone with potential antineoplastic activity.
[Uses]

DSPE-PEG Carboxylic acid (sodium), MW 2000 is a PEG-lipid that can be used in the preparation of drug delivery nanoparticles[1].
[in vivo]

DSPE-PEG Carboxylic acid (sodium), MW 2000 can prolong the blood circulation time and stability of liposomes, and enhance the targeting ability and cellular uptake efficiency of nanoparticles[1].

[References]

[1] Zhang M, et, al. Upregulating Aggregation-Induced-Emission Nanoparticles with Blood-Tumor-Barrier Permeability for Precise Photothermal Eradication of Brain Tumors and Induction of Local Immune Responses. Adv Mater. 2021 Jun;33(22):e2008802. DOI:10.1002/adma.202008802
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