ChemicalBook--->CAS DataBase List--->141-46-8

141-46-8

141-46-8 Structure

141-46-8 Structure
IdentificationBack Directory
[Name]

GLYCOLALDEHYDE
[CAS]

141-46-8
[Synonyms]

Diose
HOCH2CHO
Glycoaldehyde
GLYCOLALDEHYDE
hydroxyethanal
glycollaldehyde
2-hydroxyethanal
GLYCOLICALDEHYDE
hydroxy-acetaldehyd
Hydroxyacetaldehyde
methylolformaldehyde
2-hydroxyacetaldehyde
Methylol formaldehyde
Monomethylolformaldehyde
Acetaldehyde, hydroxy-(9CI)
141-46-8 GLYCOLALDEHYDE C2H4O2
Glycoaldehyde 2-Hydroxyacetaldehyde
Glycolaldehyde DISCONTINUED. Please see G641150
[EINECS(EC#)]

205-484-9
[Molecular Formula]

C2H4O2
[MDL Number]

MFCD00038088
[MOL File]

141-46-8.mol
[Molecular Weight]

60.05
Chemical PropertiesBack Directory
[Melting point ]

97°C
[Boiling point ]

35.05°C (rough estimate)
[density ]

1.3660
[refractive index ]

1.4772
[pka]

13.34±0.10(Predicted)
[LogP]

-1.604 (est)
[EPA Substance Registry System]

Acetaldehyde, hydroxy- (141-46-8)
Hazard InformationBack Directory
[Definition]

ChEBI: The glycolaldehyde derived from ethylene glycol. The parent of the class of glycolaldehydes.
[Hazard]

Moderately toxic by ingestion
[Uses]

Glycolaldehyde is derived from 2,2-Diethoxyethanol (D441940), which is used in the synthesis of neooxazolomycin, part of the oxazolomycin family of antibiotics. Also used in the synthesis of pyrimidine based inhibitors of phosphodiesterase 7 (PDE7).
[Synthesis]

Glycolaldehyde was prepared as follows: formaldehyde (30 mmol) was placed in a reactor, then N,N-dimethylformamide (10 ml) was added to the reactor, amidine catalyst I-K (0.15 mmol, as shown in FIG. 2) or silica gel solid-loaded triazole catalyst A-H (

Raw materials And Preparation ProductsBack Directory
[Raw materials]

2-hydroxy-2-methylpropionaldehyde-->D-(-)-ERYTHROSE-->2-Methyl-3-buten-2-ol-->D-Mannose
[Preparation Products]

Oxazole-2-amine-->2-Aminoimidazole-->2-Pentanone, 1,3,4,5-tetrahydroxy-4-(hydroxymethyl)--->2-(2-hydroxyethoxy)acetaldehyde-->DL-ARABINOSE-->D-(-)-THREOSE-->D-Glyceraldehyde-->ERYTHRULOSE
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