| Identification | Back Directory | [Name]
H-MET-HIS-ARG-GLN-GLU-ALA-VAL-ASP-CYS-LEU-LYS-LYS-PHE-ASN-ALA-ARG-ARG-LYS-LEU-LYS-GLY-ALA-OH | [CAS]
141055-85-8 | [Synonyms]
KINASE II (281-302)
CAM KINASE II 281-302
CAM KINASE II INHIBITOR
(ALA286)-CAMK-II (281-302)
CALMODULIN KINASE II INHIBITOR
CAM KINASE II [ALA-286](281-302)
CAM Kinase II Inhibitor (281-302)
[ALA-286] CAM KINASE II (281-302)
(ALA286)-CALMODULIN-DEPENDENT PROTEIN
Calmodulin-dependent Kinase II Inhibitor from rat
(ALA286)-CALMODULIN-DEPENDENT PROTEIN KINASE II (281-302)
[ALA286]-CA2+/CALMODULIN-DEPENDENT PROTEIN KINASE II (281-302)
[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) ((Ala286)-CaMK-II (281-302))
MET-HIS-ARG-GLN-GLU-ALA-VAL-ASP-CYS-LEU-LYS-LYS-PHE-ASN-ALA-ARG-ARG-LYS-LEU-LYS-GLY-ALA
H-MET-HIS-ARG-GLN-GLU-ALA-VAL-ASP-CYS-LEU-LYS-LYS-PHE-ASN-ALA-ARG-ARG-LYS-LEU-LYS-GLY-ALA-OH
L-Alanine,L-methionyl-L-histidyl-L-arginyl-L-glutaminyl-L-α-glutamyl-L-alanyl-L-valyl-L-α-aspartyl-L-cysteinyl-L-leucyl-L-lysyl-L-lysyl-L-phenylalanyl-L-asparaginyl-L-alanyl-L-arginyl-L-arginyl-L-lysyl-L-leucyl-L-lysylglycyl- | [Molecular Formula]
C111H191N39O29S2 | [MDL Number]
MFCD00214599 | [MOL File]
141055-85-8.mol | [Molecular Weight]
2600.08 |
| Chemical Properties | Back Directory | [density ]
1.47±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C | [Sequence]
Met-His-Arg-Gln-Glu-Ala-Val-Asp-Cys-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala |
| Hazard Information | Back Directory | [Uses]
[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) is a modified fragment of calcium/calmodulin-dependent protein kinase II that contains the active domain of CaMKII and has an alanine substitution at position 286. [Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) can be used to develop more potent CaMKII inhibitors[1]. | [References]
[1] Ishida A, et al. Critical amino acid residues of AIP, a highly specific inhibitory peptide of calmodulin‐dependent protein kinase II[J]. FEBS letters, 1998, 427(1): 115-118. DOI:10.1016/s0014-5793(98)00405-0 |
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