ChemicalBook--->CAS DataBase List--->14114-46-6

14114-46-6

14114-46-6 Structure

14114-46-6 Structure
IdentificationBack Directory
[Name]

3,7-DIMETHYL-1-PROPARGYLXANTHINE
[CAS]

14114-46-6
[Synonyms]

DMPX
Nsc 242985
-1H-purine-2,6(3H,7H)
3,7-Dimethyl-1-(prop-2-yn-1-yl)
3,7-DIMETHYL-1-PROPARGYLXANTHINE
3,7-DIMETHYL-1-(2-PROPYNYL)XANTHINE
1-(2-Propynyl)-3,7-dimethylxanthine
DMPX, 3,7-Dimethyl-1-(2-propynyl)xanthine
3,7-Dimethyl-1-(2-propynyl)xanthine, DMPX
1-(2-Propynyl)-3,7-dimethyl-7H-purine-2,6(1H,3H)-dione
3,7-Dimethyl-1-(2-propynyl)-7H-purine-2,6(1H,3H)-dione
3,7-diMethyl-1-(prop-2-yn-1-yl)-1H-purine-2,6(3H,7H)-dione
3,7-DIMETHYL-1-PROPARGYLXANTHINE (DMPX) ADENOSINE ANTAGONIST
1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-1-(2-propynyl)-
3,7-Dimethyl-1-propargylxanthine,3,7-Dimethyl-1-(2-propynyl)xanthine, DMPX
[Molecular Formula]

C10H10N4O2
[MDL Number]

MFCD00078576
[MOL File]

14114-46-6.mol
[Molecular Weight]

218.21
Chemical PropertiesBack Directory
[Appearance]

White Solid
[Melting point ]

204-205°C
[storage temp. ]

-20°C Freezer
[solubility ]

DMSO: ≥15 mg/mL
[form ]

solid
[color ]

white
[CAS DataBase Reference]

14114-46-6
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Uses]

A selective A2 adenosine receptor antagonist. Pharmacology: Ki vs [3H]NECA at A2 receptors in rat striatal membranes: 11 3 uM; Ki vs [3H]CHA at A1 receptors in rat cerebral cortical membranes: 45 4 uM
[Uses]

A selective A2 adenosine receptor antagonist. Pharmacology: Ki vs [3H]NECA at A2 receptors in rat striatal membranes: 11± 3 uM; Ki vs [3H]CHA at A1 receptors in rat cerebral cortical membranes: 45 ± 4 uM.
[Biochem/physiol Actions]

3,7-Dimethyl-1-propargylxanthine (DMPX) is a caffeine analog and A2-selective adenosine receptor (AR) antagonist.
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

22-26-36
[WGK Germany ]

3
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