ChemicalBook--->CAS DataBase List--->1413431-05-6

1413431-05-6

1413431-05-6 Structure

1413431-05-6 Structure
IdentificationBack Directory
[Name]

Ivacaftor-d18
[CAS]

1413431-05-6
[Synonyms]

Ivacaftor-d18
[2H18]-Ivacaftor
Ivacaftor-d18 DISCONTINUED. Please see I940603
N-(2,4-bis(1,1,1,3,3,3-d6-2-(methyl-d3)propan-2-yl)-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide
N-[2,4-bis[1,1,1,3,3,3-hexadeuterio-2-(trideuteriomethyl)propan-2-yl]-5-hydroxyphenyl]-4-oxo-1H-quinoline-3-carboxamide
[Molecular Formula]

C24H28N2O3
[MOL File]

1413431-05-6.mol
[Molecular Weight]

392.491
Hazard InformationBack Directory
[Uses]

Ivacaftor is used in the treatment of cystic fibrosis. This is the labeled analog.
[Uses]

Ivacaftor-d18 is used in the treatment of cystic fibrosis.
[Definition]

ChEBI:Ivacaftor is an aromatic amide obtained by formal condensation of the carboxy group of 4-oxo-1,4-dihydroquinoline-3-carboxylic acid with the amino group of 5-amino-2,4-di-tert-butylphenol. Used for the treatment of cystic fibrosis. It has a role as a CFTR potentiator and an orphan drug. It is a quinolone, a member of phenols, an aromatic amide and a monocarboxylic acid amide.
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