141392-23-6

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141392-23-6 Structure

Identification	Back Directory
[Name] Rapamycin, 32-O-demethyl-
[CAS] 141392-23-6
[Synonyms] 32-O-Demethyl-rapamycin Rapamycin, 32-O-demethyl- Rapamycin, 32-O-demethyl- (9CI) 32-O-Demethyl-rapamycin DISCONTINUED
[Molecular Formula] C50H77NO13
[MOL File] 141392-23-6.mol
[Molecular Weight] 900.16

Chemical Properties	Back Directory
[Boiling point ] 974.8±75.0 °C(Predicted)
[density ] 1.20±0.1 g/cm3(Predicted)
[pka] 10.40±0.70(Predicted)

Safety Data	Back Directory
[Symbol(GHS) ] GHS08
[Signal word ] Warning
[Hazard statements ] H341
[Precautionary statements ] P201-P202-P281-P308+P313-P405-P501

Hazard Information	Back Directory
[Uses] 27-O-Demethylrapamycin, a Rapamycin (HY-10219) derivative, is an antifungal agent. 27-O-Demethylrapamycin inhibits Candida albicans, Saccharomyces cerevisiae, and Fusarium oxysporum[1].
[References] [1] Wong GK, et al. Antifungal activities of rapamycin and its derivatives, prolylrapamycin, 32-desmethylrapamycin, and 32-desmethoxyrapamycin. J Antibiot (Tokyo). 1998 May;51(5):487-91. DOI:10.7164/antibiotics.51.487

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