| Identification | Back Directory | [Name]
3-Boc-3-azaspiro[5.5]undecane-9-carbaldehyde | [CAS]
1416176-14-1 | [Synonyms]
3-Boc-3-azaspiro[5.5]undecane-9-carbaldehyde
3-Boc-3-azaspiro[5.5]undecane-9-carbaldehyde - A10745
tert-butyl 9-formyl-3-azaspiro[5.5]undecane-3-carboxylate | [Molecular Formula]
C16H27NO3 | [MDL Number]
MFCD26959105 | [MOL File]
1416176-14-1.mol | [Molecular Weight]
281.39 |
| Chemical Properties | Back Directory | [Boiling point ]
385.8±42.0 °C(Predicted) | [density ]
1.06±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C, stored under nitrogen | [form ]
Solid-Liquid Mixture | [pka]
-0.92±0.40(Predicted) | [color ]
Colorless to off-white | [InChI]
InChI=1S/C16H27NO3/c1-15(2,3)20-14(19)17-10-8-16(9-11-17)6-4-13(12-18)5-7-16/h12-13H,4-11H2,1-3H3 | [InChIKey]
AXUPGUGFMSYTMC-UHFFFAOYSA-N | [SMILES]
C1C2(CCC(C=O)CC2)CCN(C(OC(C)(C)C)=O)C1 |
| Hazard Information | Back Directory | [Uses]
3-Boc-3-azaspiro[5.5]undecane-9-carbaldehyde is a PROTAC linker, and can be used for synthesis of PROTAC SOS1 degrader-8 (HY-161634)[1]. | [References]
[1] Ye Zhengqing, et al. Sos1 protein degradation agent and use thereof. Patent. WO2024083257A1 |
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SPIRO PHARMA
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www.spiropharma.com.cn |
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Cool Pharm, Ltd
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