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1416275-32-5

1416275-32-5 Structure

1416275-32-5 Structure
IdentificationBack Directory
[Name]

16:0 cholesteryl-d7 ester
[CAS]

1416275-32-5
[Synonyms]

16:0 cholesteryl-d7 ester
[Molecular Formula]

C43H76O2
[MOL File]

1416275-32-5.mol
[Molecular Weight]

625.08
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

Chloroform: Sparingly Soluble: 1-10 mg/ml
[form ]

powder
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

16:0 Cholesteryl-d7 Ester is used in biochemical methods studies to measure the cellular and medium content of [d7] cholesterol and unlabeled cholesterol that can be used to measure cholesterol efflux from cell lines which done with the addition of stable isotopes and mass spectrometry.
[Biological Activity]

Cholesteryl palmitate is associated with atherosclerotic plaque. Deuterated cholesteryl palmitate in used in reconstituting high-density lipoprotein (HDL). An elevated levels of the ratio of cholesteryl oleate to cholesteryl palmitate is implicated with apoptotic cell death in the atherosclerotic lesions.
[References]

[1] WARD E SHINE  James P M. Polar lipids in human meibomian gland secretions.[J]. Current Eye Research, 2003, 26 2: 89-94. DOI: 10.1076/ceyr.26.2.89.14515
[2] JACK LUDMIR M.D. Cholesteryl palmitate as a predictor of fetal lung maturity[J]. American journal of obstetrics and gynecology, 1987, 157 1: Pages 84-88. DOI: 10.1016/s0002-9378(87)80351-4
[3] J LUDMIR. Amniotic fluid cholesteryl palmitate in pregnancies complicated by diabetes mellitus.[J]. Obstetrics and gynecology, 1988, 72 3 Pt 1: 360-362.
[4] NAOKO FUKUHARA . Cholesteryl palmitate crystals in bronchoalveolar lavage fluid smears as a possible prognostic biomarker for chronic interstitial pneumonia: A preliminary study[J]. Respiratory investigation, 2016, 54 2: Pages 109-115. DOI: 10.1016/j.resinv.2015.09.003
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