| Identification | Back Directory | [Name]
1H-Indole-3-methanamine, N-decyl-1-[3-(dimethylamino)propyl]- | [CAS]
1416313-72-8 | [Synonyms]
Dynole 2-24
1H-Indole-3-methanamine, N-decyl-1-[3-(dimethylamino)propyl]- | [Molecular Formula]
C24H41N3 | [MOL File]
1416313-72-8.mol | [Molecular Weight]
371.6 |
| Chemical Properties | Back Directory | [Boiling point ]
495.0±30.0 °C(Predicted) | [density ]
0.96±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Oil | [pka]
10.27±0.19(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
Dynole 2-24 is an indole-based dynamin GTPase inhibitor (IC50=0.56 μM for dynamin I). Dynole 2-24 is nontoxic and shows increased potency against dynamin I and II in vitro and in cells (IC??(CME)=1.9 μM). Dynole 2-24 also shows 4.4-fold selectivity for dynamin I. Dynole 2-24 is active in-cell inhibitor of clathrin-mediated endocytosis[1]. CME: Clathrin mediated endocytosis | [storage]
Store at -20°C |
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