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1420-08-2

1420-08-2 Structure

1420-08-2 Structure
IdentificationBack Directory
[Name]

desacetamidocolchicine
[CAS]

1420-08-2
[Synonyms]

Deacetamidocolchicine
desacetamidocolchicine
Deacetylaminocolchicine
Desacetylaminocolchicine
6,7-Dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one
Benzo[a]heptalen-9(5H)-one, 6,7-dihydro-1,2,3,10-tetramethoxy-
[Molecular Formula]

C20H22O5
[MOL File]

1420-08-2.mol
[Molecular Weight]

342.39
Hazard InformationBack Directory
[Description]

Desacetamidocolchicine (DAAC) is a colchicine analogue that lacks the acetamido side chain in the ring-B of colchicine. Unlike colchicine, it binds to tubulin very quickly, and yet it has powerful antimitotic properties. It has been demonstrated that the beta-tubulin isoforms differ significantly in their interactions with colchicine.
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