ChemicalBook--->CAS DataBase List--->1421312-36-8

1421312-36-8

1421312-36-8 Structure

1421312-36-8 Structure
IdentificationBack Directory
[Name]

methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate
[CAS]

1421312-36-8
[Synonyms]

ROXA-022
Roxadustat Impurity 9
Roxadustat Impurities4
Roxadustat Methyl Ester
methyl (4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)glycinate
methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate
Glycine, N-[(4-hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]-, methyl ester
Roxadustat Impurity 2Q: What is Roxadustat Impurity 2 Q: What is the CAS Number of Roxadustat Impurity 2
[Molecular Formula]

C20H18N2O5
[MDL Number]

MFCD34184479
[MOL File]

1421312-36-8.mol
[Molecular Weight]

366.37
Chemical PropertiesBack Directory
[InChI]

InChI=1S/C20H18N2O5/c1-12-16-10-14(27-13-6-4-3-5-7-13)8-9-15(16)19(24)18(22-12)20(25)21-11-17(23)26-2/h3-10,24H,11H2,1-2H3,(H,21,25)
[InChIKey]

QSGJZCCNTOCDRI-UHFFFAOYSA-N
[SMILES]

C(OC)(=O)CNC(C1=C(O)C2=C(C(C)=N1)C=C(OC1=CC=CC=C1)C=C2)=O
Hazard InformationBack Directory
[Uses]

Roxadustat Methyl Ester is used in the preparation of Roxadustat.Roxadustat (H948180) is a hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor used to increase white blood cell levels in blood and hematopoietic progenitor cells in bone marrow.It is used for treatment of anemia in patient with chronic kidney disease.
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