| Identification | Back Directory | [Name]
N-BOC-4-PIPERIDINEACETALDEHYDE | [CAS]
142374-19-4 | [Synonyms]
tert-Butyl 4-(2-oxoethyl)
n-boc-4-piperidineacetaldehyde
1-Boc-4-(2-oxo-ethyl)piperidine
1-PIPERIDINE CARBOXYLIC ACID, 4-(2
N-Boc-4-piperidineacetaldehyde 97%
2-(N-BOC-4-piperidinyl)acetaldehyde
tert-butyl 4-(2-oxoethyl)piperidin-1-carboxylate
tert-butyl 4-(2-oxoethyl)piperidine-1-carboxylate
1-PIPERIDINE CARBOXYLIC ACID, 4-(2-OXOETHYL)-1,1-D
1-(tert-butyloxycarbonyl)-piperidine-4-acetaldehyde
tert-Butyl 4-(formylmethyl)piperidine-1-carboxylate
1-Piperidinecarboxylic acid, 4-(2-oxoethyl)-, 1,1-diMethylethyl ester
N-Boc-4-piperidineacetaldehyde/tert-butyl 4-(2-oxoethyl)piperidine-1-carboxylate | [Molecular Formula]
C12H21NO3 | [MDL Number]
MFCD03425258 | [MOL File]
142374-19-4.mol | [Molecular Weight]
227.3 |
| Chemical Properties | Back Directory | [Melting point ]
38-42 °C | [Boiling point ]
318.1±15.0 °C(Predicted) | [density ]
1.035±0.06 g/cm3(Predicted) | [Fp ]
>110℃ | [storage temp. ]
Inert atmosphere,Store in freezer, under -20°C | [form ]
solid | [pka]
-1.62±0.40(Predicted) | [Appearance]
Colorless to light yellow <38°C Solid,>42°C Liquid | [Major Application]
peptide synthesis | [InChI]
InChI=1S/C12H21NO3/c1-12(2,3)16-11(15)13-7-4-10(5-8-13)6-9-14/h9-10H,4-8H2,1-3H3 | [InChIKey]
PSRHRFNKESVOEL-UHFFFAOYSA-N | [SMILES]
N1(C(OC(C)(C)C)=O)CCC(CC=O)CC1 |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
36/37/38 | [Safety Statements ]
26 | [WGK Germany ]
3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Uses]
N-Boc-4-piperidineacetaldehyde is used in the preparation of benzofuran-2-carboxylic acid based Pim-1 inhibitors.
| [Uses]
Reactant for synthesis of:
- Pim-1 inhibitors
- Selective GPR119 agonists for type II diabetes
Reactant for:
- α-arylation of aldehydes
- Enantioselective α-benzylation of aldehydes via photoredox organocatalysis
- Enantioselective α?triflouromethylation of aldehydes
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