| Identification | Back Directory | [Name]
3'-DEOXY-3'-IODOTHYMIDINE | [CAS]
14260-82-3 | [Synonyms]
3'-IODOTHYMIDINE
3'-DEOXY-3'-IODOTHYMIDINE
THYMIDINE, 3'-DEOXY-3'-IODO
3'-Iodo-3'-deoxy-D-thymidine | [Molecular Formula]
C10H13IN2O4 | [MDL Number]
MFCD08061409 | [MOL File]
14260-82-3.mol | [Molecular Weight]
352.13 |
| Chemical Properties | Back Directory | [Appearance]
Colourless solid | [Melting point ]
165.5-166 °C(Solv: water (7732-18-5)) | [density ]
1.91±0.1 g/cm3(Predicted) | [pka]
9.55±0.10(Predicted) |
| Hazard Information | Back Directory | [Chemical Properties]
Colourless solid | [Uses]
3′-Deoxy-3′-iodothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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