ChemicalBook--->CAS DataBase List--->1426173-48-9

1426173-48-9

1426173-48-9 Structure

1426173-48-9 Structure
IdentificationBack Directory
[Name]

Cefprozil-d4 (E/Z mixture)
[CAS]

1426173-48-9
[Synonyms]

Cefzil-d4
Procef-d4
Prozef-d4
BMY 28100-d4
Cefprozile-d4
Cephprozyl-d4
Cefprozil-d4 (E/Z mixture)
(6R,7R)-7-[[(2R)-2-AMino-2-(4-hydroxyphenyl-d4)acetyl]aMino]-8-oxo-3-(1-propen-1-yl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
[Molecular Formula]

C18H19N3O5S
[MOL File]

1426173-48-9.mol
[Molecular Weight]

389.43
Chemical PropertiesBack Directory
[solubility ]

DMSO: soluble
Methanol: soluble
Water: soluble
Hazard InformationBack Directory
[Uses]

Labelled Cefprozil. Semisynthetic oral cephalosporin consisting of approx. 90:10 Z/E isomeric mixture. Antibacterial.
[IC 50]

β-lactam
[References]

[1] K TOMATSU. In vitro and in vivo evaluations of BMY-28100, a new oral cephalosporin.[J]. Journal of Antibiotics, 1987, 40 8: 1175-1183. DOI: 10.7164/antibiotics.40.1175
[2] MIHAELA PERIC BS . Activity of nine oral agents against gram-positive and gram-negative bacteria encountered in community-acquired infections: Use of pharmacokinetic/pharmacodynamic breakpoints in the comparative assessment of beta-lactam and macrolide antimicrobial agents[J]. Clinical therapeutics, 2003, 25 1: Pages 169-177. DOI: 10.1016/s0149-2918(03)90021-x
[3] K. NAGAI. Effects of Amino Acid Alterations in Penicillin-Binding Proteins (PBPs) 1a, 2b, and 2x on PBP Affinities of Penicillin, Ampicillin, Amoxicillin, Cefditoren, Cefuroxime, Cefprozil, and Cefaclor in 18 Clinical Isolates of Penicillin-Susceptible, -Intermediate, and -Resistant Pneumococci[J]. Antimicrobial Agents and Chemotherapy, 2002, 46 1: 1273-1280. DOI: 10.1128/aac.46.5.1273-1280.2002
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