1426309-31-0

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1426309-31-0 Structure

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[Name] 6H-Pyrrolo[2,3-d]pyrimidin-6-one, 4-amino-2-[5-fluoro-1-[(2-fluorophenyl)methyl]-6-methyl-1H-pyrazolo[3,4-b]pyridin-3-yl]-5,7-dihydro-5,5-dimethyl-
[CAS] 1426309-31-0
[Synonyms] SGC agonist 1 6H-Pyrrolo[2,3-d]pyrimidin-6-one, 4-amino-2-[5-fluoro-1-[(2-fluorophenyl)methyl]-6-methyl-1H-pyrazolo[3,4-b]pyridin-3-yl]-5,7-dihydro-5,5-dimethyl-
[Molecular Formula] C22H19F2N7O
[MOL File] 1426309-31-0.mol
[Molecular Weight] 435.43

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[Uses] SGC agonist 1 is a potent agonist of soluble guanylate cyclase (SGC). SGC agonist 1 improves solubility combined with high cell permeability. SGC agonist 1 has the potential for the research of cardiovascular disease (extracted from patent WO2016030354A1, compound 18A)[1].
[References] [1] Alexandros Vakalopoulos, et al. Amino-substituted annulated pyrimidines and use thereof. Patent WO2016030354A1.

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