| Identification | Back Directory | [Name]
(S)-(5-Methyl-3-phenyl-1,3-dihydropyrrolo[1,2-c]thiazole-6,7-diyl)dimethanol | [CAS]
1426937-93-0 | [Synonyms]
p53 Activator 8
(S)-(5-Methyl-3-phenyl-1,3-dihydropyrrolo[1,2-c]thiazole-6,7-diyl)dimethanol |
| Hazard Information | Back Directory | [Uses]
p53 Activator 8 (compound 5) is a p53 activator. p53 Activator 8 has potent anti-proliferative activity against MCF7 breast cancer cell lines with an IC50 value of 0.5 μM[1][2]. | [References]
[1] ATAíDE SARAIVA, et al. WO2019243906. 2019.
[2] Maria I L Soares, et al. Chiral 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles with anti-breast cancer properties. Eur J Med Chem. 2013. DOI:10.1016/j.ejmech.2012.11.036 |
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