| Identification | Back Directory | [Name]
3-(3-Bromo-4-hydroxyphenyl)-1-(2,4-dihydroxyphenyl)-2-propen-1-one | [CAS]
1429522-04-2 | [Synonyms]
DAPK1-IN-1
3-(3-Bromo-4-hydroxyphenyl)-1-(2,4-dihydroxyphenyl)-2-propen-1-one | [Molecular Formula]
C15H11BrO4 | [MOL File]
1429522-04-2.mol | [Molecular Weight]
335.15 |
| Chemical Properties | Back Directory | [Boiling point ]
515.3±50.0 °C(Predicted) | [density ]
1.664±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [pka]
7.30±0.35(Predicted) |
| Hazard Information | Back Directory | [Uses]
DAPK1-IN-1 (compound 10) is a death-associated protein kinase 1 (DAPK1) inhibitor with a Kd value of 0.63 μM. DAPK1-IN-1 can be used in Alzheimer’s disease research[1]. | [References]
[1] Yokoyama T, et al. Discovery and optimization of isoliquiritigenin as a death-associated protein kinase 1 inhibitor. Eur J Med Chem. 2024 Sep 4;279:116836. DOI:10.1016/j.ejmech.2024.116836 |
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