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143077-65-0

143077-65-0 Structure

143077-65-0 Structure
IdentificationBack Directory
[Name]

D-ARG-D-PRO-LYS-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-LEU-NH2 ACETATE SALT
[CAS]

143077-65-0
[Synonyms]

(D-arg1
[D-Arg1, D-Pro2, D-Trp7,9, Leu11]-Substance acetate salt
[D-ARG1, D-PRO2, D-TRP7,9, LEU11]-SUBSTANCE P ACETATE SALT
D-ARG-D-PRO-LYS-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-LEU-NH2 ACETATE SALT
[Molecular Formula]

C77H112N20O15
[MDL Number]

MFCD00133837
[MOL File]

143077-65-0.mol
[Molecular Weight]

1557.84
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[Sequence]

{D-Arg}-{D-Pro}-Lys-Pro-Gln-Gln-{D-Trp}-Phe-{D-Trp}-Leu-Leu-NH2
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P (acetate) is an antagonist for Substance P (HY-P0201) and Bombesin (HY-P0195) that has effects on ocular inflammatory responses to antidromic trigeminal nerve stimulation[1].
[References]

[1] A Mandahl, A Bill, et al. Effects of the substance P antagonist, (D-Arg1, D-Pro2, D-Trp7,9, Leu11)-SP on the miotic response to substance P, antidromic trigeminal nerve stimulation, capsaicin, prostaglandin E1, compound 48/80 and histamine. Acta Physiol Scand. 1984 Jan;120(1):27-35. DOI:10.1111/j.1748-1716.1984.tb07369.x
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