| Identification | Back Directory | [Name]
Cycloechinulin | [CAS]
143086-29-7 | [Synonyms]
Cycloechinulin Pyrazino[1',2':1,2]azocino[5,4-b]indole-1,4-dione, 2,3,8,9-tetrahydro-11-methoxy-3,8,8-trimethyl-, (3S)- | [Molecular Formula]
C20H21N3O3 | [MOL File]
143086-29-7.mol | [Molecular Weight]
351.4 |
| Chemical Properties | Back Directory | [Boiling point ]
675.0±55.0 °C(Predicted) | [density ]
1.33±0.1 g/cm3(Predicted) | [solubility ]
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble | [form ]
A solid | [pka]
10.79±0.60(Predicted) |
| Hazard Information | Back Directory | [Description]
Cycloechinulin is a diketopiperazine fungal metabolite originally isolated from A. ochraceus. It reduces weight gain of corn earworms by 33% compared to controls when used at a dose of 100 ppm in the diet. | [Uses]
Cycloechinulin is a diketopiperazine natural product. | [Uses]
Cycloechinulin is an unusual diketopiperazine isolated from Aspergillus ochraceus. Cycloechinulin has not been extensively studied but exhibits insecticidal activity against the lepidopteran crop pest, Helicoverpa zea. Recently, cycloechinulin has found use as a secondary metabolite standard for polyphasic taxonomy in Aspergillus. | [IC 50]
Microbial Metabolite | [References]
[1] FLORECITA S. DE GUZMAN. New Diketopiperazine Metabolites from the Sclerotia of Aspergillus ochraceus[J]. Journal of Natural Products , 1992, 55 7: 931-939. DOI: 10.1021/np50085a013 |
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