| Identification | Back Directory | [Name]
verazine | [CAS]
14320-81-1 | [Synonyms]
verazine
20-epi-Verazine
（20R,20S）-Verazine
(20R)-20-[[(S)-3,4,5,6-Tetrahydro-5-methylpyridin]-2-yl]pregn-5-en-3β-ol
Pregn-5-en-3-ol, 20-[(5S)-3,4,5,6-tetrahydro-5-methyl-2-pyridinyl]-, (3β,20S)- | [Molecular Formula]
C27H43NO | [MOL File]
14320-81-1.mol | [Molecular Weight]
397.65 |
| Chemical Properties | Back Directory | [Melting point ]
175-177 °C | [Boiling point ]
510.9±23.0 °C(Predicted) | [density ]
1.19±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
15.03±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
This alkaloid occurs in Veratrum album subsp. lobelianum. The structure given
above has been confirmed by synthesis of the alkaloid. | [Uses]
Verazine ((-)-Verazine) is an anti-Fungal Agent that can be found in the dried roots and rhizoma of Veratrum maackii Regel. Verazine causes DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. Verazine can be used in the study of fungal infections and neurological diseases[1][2]. | [References]
Guenter Adam, Schreiber, Tomko., Justus Liebig's Ann. Chem., 707,203
( 1967) |
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