| Identification | Back Directory | [Name]
L-Glutamic acid, glycyl-L-asparaginyl-L-isoleucyl-L-phenylalanyl-L-alanyl-L-asparaginyl-L-leucyl-L-phenylalanyl-L-lysylglycyl-L-leucyl-L-phenylalanylglycyl-L-lysyl-L-lysyl- | [CAS]
143228-35-7 | [Synonyms]
L-Glutamic acid, glycyl-L-asparaginyl-L-isoleucyl-L-phenylalanyl-L-alanyl-L-asparaginyl-L-leucyl-L-phenylalanyl-L-lysylglycyl-L-leucyl-L-phenylalanylglycyl-L-lysyl-L-lysyl- | [Molecular Formula]
C85H131N21O21 | [MOL File]
143228-35-7.mol | [Molecular Weight]
1783.08 |
| Chemical Properties | Back Directory | [Boiling point ]
2003.2±65.0 °C(predicted) | [density ]
1.258±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
3.16±0.10(predicted) | [Sequence]
Gly-Asn-Ile-Phe-Ala-Asn-Leu-Phe-Lys-Gly-Leu-Phe-Gly-Lys-Lys-Glu |
| Hazard Information | Back Directory | [Uses]
ARF1 (2-17) inhibits both ARF-independent (PLC-β) and ARF-dependent (PLD) pathways. ARF1 (2-17) inhibits GTP-γ-S-stimulated PLD activity, phospholipase C-β (PLC-β), and exocytosis[1]. | [References]
[1] Fensome A, et al. ARF1(2-17) does not specifically interact with ARF1-dependent pathways. Inhibition by peptide of phospholipases C beta, D and exocytosis in HL60 cells. FEBS Lett. 1994 Jul 25;349(1):34-8. DOI:10.1016/0014-5793(94)00634-2 |
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