| Identification | Back Directory | [Name]
oxazole yellow | [CAS]
143413-86-9 | [Synonyms]
oxazole yellow
1-Methyl-4-((3-methyl-2(3H)-benzoxazolylidene)methyl)-quinolinium iodide
Quinolinium, 1-methyl-4-((3-methyl-2(3H)-benzoxazolylidene)methyl)-, iodide | [Molecular Formula]
C19H17IN2O | [MDL Number]
MFCD28900761 | [MOL File]
143413-86-9.mol | [Molecular Weight]
416.256 |
| Hazard Information | Back Directory | [Uses]
Oxazole yellow is a cyanine dye composed of benzoxazole and quinoline rings connected by a linker. It is almost non-luminescent in water, but its green fluorescence is significantly enhanced after intercalation in double-stranded DNA. Oxazole yellow can be used to detect cell apoptosis[1][2][3]. | [References]
[1] Jin C, et al. Molecular Dynamics of Oxazole Yellow Dye in its Ground and First Excited Electronic States in Solution and when Intercalated in dsDNA[J]. The Journal of Physical Chemistry B, 2017, 121(44): 10242-10248. DOI:10.1021/acs.jpcb.7b08187
[2] Zhu H, et al. High-sensitivity capillary electrophoresis of double-stranded DNA fragments using monomeric and dimeric fluorescent intercalating dyes[J]. Analytical chemistry, 1994, 66(13): 1941-1948. DOI:10.1021/ac00085a004
[3] Eriksson M, et al. Binding of intercalating and groove-binding cyanine dyes to bacteriophage T5[J]. The journal of physical chemistry B, 2007, 111(5): 1139-1148. DOI:10.1021/jp064322m |
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