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143442-54-0

143442-54-0 Structure

143442-54-0 Structure
IdentificationBack Directory
[Name]

9(S)-HODE CHOLESTERYL ESTER
[CAS]

143442-54-0
[Synonyms]

9(S)-HODE CHOLESTERYL ESTER
ALWABJCAEDQEGO-CNCQKSCYSA-N
9S-HYDROXY-10E,12Z-OCTADECADIENOIC ACID, CHOLESTERYL ESTER
Cholest-5-en-3-ol (3β)-, (9S,10E,12Z)-9-hydroxy-10,12-octadecadienoate (9CI)
[Molecular Formula]

C45H76O3
[MDL Number]

MFCD00216100
[MOL File]

143442-54-0.mol
[Molecular Weight]

665.08
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: >50 mg/ml; DMSO: >50 mg/ml; Ethanol: >50 mg/ml; Ethanol:PBS (1:10): <10 μg/ml
Safety DataBack Directory
[Symbol(GHS) ]


GHS02,GHS07
[Signal word ]

Danger
[Hazard statements ]

H225-H319
[Precautionary statements ]

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
Hazard InformationBack Directory
[Description]

9(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions.1 It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid peroxidation.2 9(S)-HODE cholesteryl ester can be used as a standard for analysis of chiral HODE cholesteryl esters.
[References]

1. Brooks, C.J.W., Harland, W.A., Steel, G., et al. Lipids of human atheroma: Isolation of hydroxyoctadecadienoic acids from advanced aortal lesions Biochim. Biophys. Acta 202(3),563-566(1970).
2. Belkner, J., Wiesner, R., Kühn, H., et al. The oxygenation of cholesterol esters by the reticulocyte lipoxygenase FEBS Lett. 279(1),110-114(1991).
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